Multimodal Analysis Generated Pathogenic Impact Evaluator

  • SpTransformer

    Tissue specific splicing prediction based on Transformer model

  • Anchored-Fusion

    The Anchored-fusion is a bioinformatic tool which detects fusion genes bases on paired-end RNA-sequence with ultrahigh sensitivity. Anchored-fusion target on the gene you choose, it will give the fusion genes including the target gene. Other fusion genes will not be represented in the output file.

  • RESA

    RESA detects somatic mutation with high precision directly from scRNA-seq data. The key assumption of this method is that cancer cells evolve in a clonal manner and thus expressed somatic mutations have cross-cell recurrence, whereas the noise and artefacts are likely distributed randomly with small probability of recurrence across the cell population. RESA is composed of three main steps: initial variant calling, filtering and labeling, and modeling and refinement.